Study record managers: refer to the Data Element Definitions if submitting registration or results information. Older people with schizophrenia suffer from greater physical comorbidity, cognitive impairment, and medication side effects compared to their younger counterparts. Unfortunately, little research is available to guide the treatment of subsyndromal depressive symptoms in older adults.
Researchers from Regenstrief Institute and Indiana University who followed over 30, older adults for a decade have found the rate of dementia diagnosis for patients with schizophrenia to be twice as high as for patients without this chronic, severe and disabling brain disorder. The reason for this difference is unclear and merits more intensive investigation. Is this related to an increase in dementia-related brain pathology or could it simply represent a misinterpretation of their symptoms by clinicians inexperienced in dealing with individuals who have difficulties communicating and are less likely to have reliable significant others to interpret for them?
The prognosis of schizophrenia is varied at the individual level. In general it has great human and economics costs. Schizophrenia is a major cause of disability.
Skip to search form Skip to main content. Treating older adults with schizophrenia: challenges and opportunities. Jeste and Jeanne E. JesteJeanne E.
As we get older, our bodies age in three ways: physically, cognitively and psychosocially. Our faces wrinkle and health deteriorates; our memories start to fail us and cognitive functions slow down; and we start to feel worse about ourselves and become more withdrawn from society and relationships. These changes are part of our human nature, however with certain preexisting illnesses, such as mental illnesses or physical ailments, aging may be a serious concern.
Schizophrenia is a brain disorder that affects the way a person behaves, thinks, and sees the world. People with paranoid schizophrenia have an altered perception of reality. This can cause relationship problems, disrupt normal daily activities like bathing, eating, or running errands, and lead to alcohol and drug abuse in an attempt to self-medicate.
Schizophrenia is a serious mental disorder in which people interpret reality abnormally. Schizophrenia may result in some combination of hallucinations, delusions, and extremely disordered thinking and behavior that impairs daily functioning, and can be disabling. People with schizophrenia require lifelong treatment.
Men display more negative symptoms such as poor social functioning, flat affect, amotivation, and poverty of speech, whereas women are prone to more positive symptoms, such as auditory hallucinations and persecutory delusions. Some studies also suggest that men have more cognitive impairment and a more severe course of illness. During the last decade, scientists have begun to recognize that male and female biology is different, and therefore findings in men cannot generalize to females.
Studies of the life course of schizophrenia suggest that positive symptoms tend to reduce with time, while negative symptoms, such as social withdrawal and emotional apathy, increase with time. In contrast, people with late-onset schizophrenia onset after 40 years of age and very late-onset schizophrenia onset after 60 years of age tend to have predominant positive symptoms and fewer negative symptoms. What is the evidence for treatments for elderly people and people with late-onset schizophrenia?